Most important of all, working with a drawing tablet is faster and more efficient than with a mouse. There are buttons on the pen that can be programmed for right click or other commands. Touching the tip of the pen on the tablet surface is the equivalent of a click, while pressure and pen tilt can be used to vary stroke width, opacity, effect intensity, and other attributes. Most professional programs on those fields offer advanced pen support and can recognize and use pen pressure and even tilt, on more feature-rich models like the Wacom Intuos Pro lineup.
Drawing tablets can be used for most creative and content production needs such as illustration, photography, 3D modeling, animation, graphic design, etc.